Article
Identification of Genotype Errors.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
O'Connell Jeffery, Yao Yin
Abstract excerpt
It has been documented that there exist some errors in most large genotype datasets and that an error rate of 1-2% is sufficient to lead to the distortion of map distance as well as a false conclusion of linkage (Abecasis et al., Eur J Hum Genet 9:130-134, 2001), therefore one needs to ensure that the data are as clean as possible. On the other hand, the process of data cleaning is tedious and demands effort and...
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