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Article

Epitheliomesenchymal transdifferentiation of cultured RPE cells.

Ophthalmic research - 1 Jan 2000

Lee S C, Kwon O W, Seong G J, Kim S H, Ahn J E, Kay E D

Abstract excerpt

Retinal pigment epithelium (RPE) cells of the proliferative vitreoretinopathy (PVR) membrane take on the shape of fibroblasts and participate in fibrosis, thus deviating from the character of epithelial cells. This study was undertaken to evaluate RPE cell transdifferentiation in vitro. During the culture of porcine RPE cells, primary and 10th-passaged RPE cells were investigated for cell growth in response to...

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Identifiers

PMID: 11244352
DOI: 10.1159/000055648

Genes

RPE
PVR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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