Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Macrophages acquire fibroblast characteristics in a rat model of proliferative vitreoretinopathy.

Ophthalmic research - 1 Jan 2011

Lin Miao-li, Li Yong-ping, Li Zhan-rong, Lin Jian-xian, Zhou Xiao-lai, Liang Dan

Abstract excerpt

PURPOSE: Our aim was to establish a rat model of proliferative vitreoretinopathy (PVR) induced by macrophages and investigate whether macrophages can be a cell origin of fibroblast-like cells present in PVR. METHODS: One eye of each rat received an intravitreal injection of macrophages. Clinical examination was performed to evaluate the development of PVR. Histological study was carried out to observe the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation, Myelomonocytic
Share to Cell Transdifferentiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glial Fibrillary Acidic Protein

Share to Intravitreal Injections

Share to Keratins

Share to Macrophages, Peritoneal

Share to Rats, Sprague-Dawley

Share to Vimentin

Source

Identifiers

PMID: 21051916
DOI: 10.1159/000320496

Genes

PVR
GFAP
VIM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Macrophages acquire fibroblast characteristics in a rat model of proliferative vitreoretinopathy.PMID 21051916Read ↗

Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathySemantic proximity Read ↗

Cellular and Fibrillar Collagen Analyses in an Animal Model of Retinal Detachment-Related Proliferative Vitreoretinopathy Reveals a Defined Transition to Chronic FibrosisSemantic proximity Read ↗

Evaluation of proliferating cell abundance and phenotypes in proliferative diabetic retinopathy.Semantic proximity Read ↗

The dynamic changes of macrophage morphology in progression of choroidal neovascularization in laser-induced choroidal neovascularization mice modelSemantic proximity Read ↗

Epithelial-mesenchymal transition-like phenotypic changes of retinal pigment epithelium induced by TGF-β are prevented by PPAR-γ agonists.Semantic proximity Read ↗

Müller cell changes precede photoreceptor cell degeneration in the age-related retinal degeneration of the Fischer 344 ratSemantic proximity Read ↗

Fibrocontractive Müller cell phenotypes in proliferative diabetic retinopathy.Semantic proximity Read ↗

Regional Alterations in Müller Cell Protein Expression in Human and a Rat Model of Geographic AtrophySemantic proximity Read ↗

Effect of Methotrexate on an In Vitro Patient-Derived Model of Proliferative Vitreoretinopathy.Semantic proximity Read ↗

TGF-β-SNAIL axis induces Müller glial-mesenchymal transition in the pathogenesis of idiopathic epiretinal membraneSemantic proximity Read ↗

A novel rat model to study the functions of macrophages during normal development and pathophysiology of the eye.Semantic proximity Read ↗

Ultrastructural and immunocytochemical changes in retinal pigment epithelium, retinal glia, and fibroblasts in vitreous culture.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.