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Article

Phenotype-associated changes in retinal pigment epithelial cell expression of insulin-like growth factor binding proteins.

Investigative ophthalmology & visual science - 1 Nov 2009

Mukherjee Sudipto, King Jeffery L, Guidry Clyde

Abstract excerpt

PURPOSE: The objectives of this study were to evaluate retinal pigment epithelial (RPE) cells as a source of insulin-like growth factor binding proteins (IGFBPs) and to characterize biosynthetic changes associated with the cell phenotype and vitreous growth factor stimuli known to be present in fibrocontractive diseases. METHODS: Early culture-associated changes in RPE phenotype were characterized by indirect...

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Source

Identifiers

PMID: 19516007
DOI: 10.1167/iovs.09-3383

Genes

RPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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