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Article

Ultrastructural and immunocytochemical changes in retinal pigment epithelium, retinal glia, and fibroblasts in vitreous culture.

Investigative ophthalmology & visual science - 1 Dec 1990

Vinores S A, Campochiaro P A, McGehee R, Orman W, Hackett S F, Hjelmeland L M

Abstract excerpt

Retinal pigment epithelial (RPE) cells, retinal glial, and fibroblasts, three cell types believed to play a role in the pathogenesis of epiretinal membrane formation, were maintained in vitreous culture to determine the influence of vitreous on their ultrastructure and expression of cytokeratin, glial fibrillary acidic protein (GFAP), vimentin, and glutamine synthetase (GS). Using a highly sensitive, preembedding...

Topics

Animals
Cattle
Cells, Cultured
Fibroblasts
Glial Fibrillary Acidic Protein
Glutamate-Ammonia Ligase
Humans
Immunoenzyme Techniques
Immunohistochemistry
Keratins
Membranes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neuroglia

Phenotype

Pigment Epithelium of Eye

Vimentin

Vitreous Body

Source

Identifiers

PMID: 1702409

Genes

RPE
GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1702409-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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