Article
Transdifferentiation of retinal pigment epithelial cells from epithelial to mesenchymal phenotype.
Investigative ophthalmology & visual science - 1 Feb 1995
Grisanti S, Guidry C
Abstract excerpt
PURPOSE: To describe and evaluate retinal pigment epithelial (RPE) cell transdifferentiation in vitro and to determine its importance to the development of proliferative vitreoretinal disorders. METHODS: Porcine RPE cells from single animals were examined at different passages in culture. The authors examined cellular morphology, contraction of a collagenous matrix, and adhesion to fibronectin and type I...
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