Transdifferentiation of retinal pigment epithelial cells from epithelial to mesenchymal phenotype.

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Article

Transdifferentiation of retinal pigment epithelial cells from epithelial to mesenchymal phenotype.

Investigative ophthalmology & visual science - 1 Feb 1995

Grisanti S, Guidry C

Abstract excerpt

PURPOSE: To describe and evaluate retinal pigment epithelial (RPE) cell transdifferentiation in vitro and to determine its importance to the development of proliferative vitreoretinal disorders. METHODS: Porcine RPE cells from single animals were examined at different passages in culture. The aut...

Topics

Actins
Animals
Cell Adhesion
Cell Differentiation
Cells, Cultured
Collagen
Epithelial Cells
Epithelium
Fibronectins
Fluorescent Antibody Technique
Keratins
Mesoderm
Phenotype
Pigment Epithelium of Eye
Swine
Vitreoretinopathy, Proliferative

Source

Open in PubMed

Identifiers

PMID: 7531185

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7531185-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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