Article
Loss of palindromic symmetry in Tg.AC mice with a nonresponder phenotype.
Molecular carcinogenesis - 1 Feb 2001
Honchel R, Rosenzweig B A, Thompson K L, Blanchard K T, Furst S M, Stoll R E, Sistare F D
Abstract excerpt
The Tg.AC transgenic mouse carries the v-Ha-ras oncogene under the control of the zeta-globin promoter and is currently being used in a short-term carcinogenesis assay for safety testing of pharmaceuticals. A subset of hemizygous Tg.AC mice was found to be nonresponsive to the tumor promoter 12-O...
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