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Article

Genetic polymorphism of paraoxonase 1 (PON1) and susceptibility to Parkinson's disease.

Brain research - 28 Sept 1998

Kondo I, Yamamoto M

Abstract excerpt

Toxicologists have thought that the paraoxonase (PON) enzyme polymorphism might contribute to effects of pollutants and other environmental chemicals on susceptibility to cancer, birth defects and Parkinson's disease (PD). We studied a biallelic PON1 polymorphism at codon 192 (A and B alleles) in 166 patients with sporadic idiopathic PD. The frequency of the B (Arg) allele of PON1 was significantly increased in...

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Source

Identifiers

PMID: 9739148
DOI: 10.1016/s0006-8993(98)00586-1

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic polymorphism of paraoxonase 1 (PON1) and susceptibility to Parkinson's disease.PMID 9739148Read ↗

Association of Paraoxonse1 (PON1) Genotypes with the Activity of PON1 in Patients with Parkinson's Disease.Semantic proximity Read ↗

Association of a protective paraoxonase 1 (PON1) polymorphism in Parkinson's disease.Semantic proximity Read ↗

Paraoxonase 1 Met--Leu 54 polymorphism is associated with Parkinson's disease.Semantic proximity Read ↗

Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism.Semantic proximity Read ↗

Paraoxonase 1 polymorphisms L55M and Q192R were not risk factors for Parkinson's disease: a HuGE review and meta-analysis.Semantic proximity Read ↗

No association between paraoxonase 1 (PON1) gene polymorphisms and susceptibility to Parkinson's disease in a Chinese population.Semantic proximity Read ↗

Further evidence for an association of the paraoxonase 1 (PON1) Met-54 allele with Parkinson's disease.Semantic proximity Read ↗

Gln192Arg polymorphism in paraoxonase 1 gene is associated with Alzheimer disease in a Chinese Han ethnic population.Semantic proximity Read ↗

Paraoxonase 1 (PON1) gene polymorphisms and Parkinson's disease in a Finnish population.Semantic proximity Read ↗

Role of paraoxonase 1 (PON1) in organophosphate metabolism: implications in neurodegenerative diseases.Semantic proximity Read ↗

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