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Article

Paraoxonase 1 polymorphisms L55M and Q192R were not risk factors for Parkinson's disease: a HuGE review and meta-analysis.

Gene - 15 Jun 2012

Liu Ying-Li, Yang Jie, Zheng Jie, Liu Dian-Wu, Liu Tian, Wang Jian-Min, Wang Chao-Nan, Wang Ming-Wei, Tian Qing-Bao

Abstract excerpt

PURPOSE: The Paraoxonase 1 (PON1) has been studied as a potential candidate gene for Parkinson's disease risk, but direct evidence from genetic association studies remains inconclusive. We performed a meta-analysis pooling data from all relevant studies in order to determine the effects of two PON 1 polymorphisms (L55M and Q192R) on Parkinson's disease. METHODS: We applied a random effects to combine odds ratio...

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Source

Identifiers

PMID: 22521594
DOI: 10.1016/j.gene.2012.03.067

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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