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Article

Functional phosphorylation sites in the C-terminal region of the multivalent multifunctional transcriptional factor CTCF.

Molecular and cellular biology - 1 Mar 2001

Klenova E M, Chernukhin I V, El-Kady A, Lee R E, Pugacheva E M, Loukinov D I, Goodwin G H, Delgado D, Filippova G N, León J, Morse H C, Neiman P E, Lobanenkov V V

Abstract excerpt

CTCF is a widely expressed and highly conserved multi-Zn-finger (ZF) nuclear factor. Binding to various CTCF target sites (CTSs) is mediated by combinatorial contributions of different ZFs. Different CTSs mediate distinct CTCF functions in transcriptional regulation, including promoter repression or activation and hormone-responsive gene silencing. In addition, the necessary and sufficient core sequences of...

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Identifiers

PMID: 11238955
DOI: 10.1128/MCB.21.6.2221-2234.2001
PMCID: PMC86856

Genes

CTCF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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