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Article

Regulation of the transcription factor, CTCF, by phosphorylation with protein kinase CK2.

FEBS letters - 28 Feb 2005

El-Kady Ayman, Klenova Elena

Abstract excerpt

CTCF is a transcription factor involved in various aspects of gene regulation. We previously reported that CTCF function is modulated by protein kinase CK2. In this report we investigate further the role of CK2 in regulating the transcriptional properties of CTCF. We demonstrate that coexpression of CTCF with CK2 switches function of CTCF from repressor to activator. The non-phosphorylatable mutant increases...

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Source

Identifiers

PMID: 15733852
DOI: 10.1016/j.febslet.2005.01.044

Genes

CTCF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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