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Article

Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts.

Nature - 2 Dec 1999

Wodarz A, Ramrath A, Kuchinke U, Knust E

Abstract excerpt

Asymmetric cell division generates daughter cells with different developmental fates from progenitor cells that contain localized determinants. During this division, the asymmetric localization of cell-fate determinants and the orientation of the mitotic spindle must be precisely coordinated. In Drosophila neuroblasts, inscuteable controls both spindle orientation and the asymmetric localization of the cell-fate...

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Identifiers

PMID: 10591216
DOI: 10.1038/990128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts.PMID 10591216Read ↗

Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts.Semantic proximity Read ↗

Role of inscuteable in orienting asymmetric cell divisions in Drosophila.Semantic proximity Read ↗

Bazooka is required for localization of determinants and controlling proliferation in the sensory organ precursor cell lineage in Drosophila.Semantic proximity Read ↗

Identification of Miranda protein domains regulating asymmetric cortical localization, cargo binding, and cortical release.Semantic proximity Read ↗

Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila.Semantic proximity Read ↗

cdc2 links the Drosophila cell cycle and asymmetric division machineries.Semantic proximity Read ↗

The Partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila.Semantic proximity Read ↗

Control of spindle orientation in Drosophila by the Par-3-related PDZ-domain protein Bazooka.Semantic proximity Read ↗

Membrane targeting of Bazooka/PAR-3 is mediated by direct binding to phosphoinositide lipids.Semantic proximity Read ↗

miranda localizes staufen and prospero asymmetrically in mitotic neuroblasts and epithelial cells in early Drosophila embryogenesis.Semantic proximity Read ↗

Going vertical: functional role and working principles of the protein Inscuteable in asymmetric cell divisions.Semantic proximity Read ↗

A mouse homologue of Drosophila pins can asymmetrically localize and substitute for pins function in Drosophila neuroblasts.Semantic proximity Read ↗

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