Article
Evidence for inflammatory bowel disease of a susceptibility locus on the X chromosome.
Gastroenterology - 1 Mar 2001
Vermeire S, Satsangi J, Peeters M, Parkes M, Jewell D P, Vlietinck R, Rutgeerts P
Abstract excerpt
BACKGROUND & AIMS: The technique of genomewide scanning has been applied successfully in inflammatory bowel disease (IBD). A number of putative susceptibility loci have been identified through genomewide searches including replicated regions of linkage on chromosomes 12, 16, 6 (the HLA region), and 14. We have investigated the contribution of the X chromosome in 145 Belgian affected relative pairs. METHODS: In...
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