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Article

Mapping susceptibility loci in inflammatory bowel disease: why and how?

Molecular medicine today - 1 Dec 1997

Parkes M, Satsangi J, Jewell D

Abstract excerpt

The cause of the inflammatory bowel diseases Crohn's disease and ulcerative colitis is unknown, but epidemiological evidence suggests that it is multifactorial with a strong genetic component. Several genetic loci probably contribute to disease susceptibility, accounting for the complex pattern of inheritance and heterogeneous clinical manifestations. The combination of candidate gene studies and, more recently,...

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PMID: 9449126
DOI: 10.1016/S1357-4310(97)01134-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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