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Article

Alkaline-mediated differential interaction (AMDI): a simple automatable single-nucleotide polymorphism assay.

Proceedings of the National Academy of Sciences of the United States of America - 27 Feb 2001

Bartlett S, Straub J, Tonks S, Wells R S, Bodmer J G, Bodmer W F

Abstract excerpt

The key requirements for high-throughput single-nucleotide polymorphism (SNP) typing of DNA samples in large-scale disease case-control studies are automatability, simplicity, and robustness, coupled with minimal cost. In this paper we describe a fluorescence technique for the detection of SNPs that have been amplified by using the amplification refractory mutation system (ARMS)-PCR procedure. Its performance was...

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Identifiers

PMID: 11226301
DOI: 10.1073/pnas.041619998
PMCID: PMC30200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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