Article
Detection of allelic variations of human gene expression by polymerase colonies.
BMC genetics - 16 Feb 2004
Butz James A, Yan Hai, Mikkilineni Venugopal, Edwards Jeremy S
Abstract excerpt
BACKGROUND: Quantification of variations of human gene expression is complicated by the small differences between different alleles. Recent work has shown that variations do exist in the relative allelic expression levels in certain genes of heterozygous individuals. Herein, we describe the application of an immobilized polymerase chain reaction technique as an alternative approach to measure relative allelic...
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