Article
Invasive reaction assisted strand-displacement signal amplification for sensitive DNA detection.
Chemical communications (Cambridge, England) - 18 Nov 2014
Zou Bingjie, Song Qinxin, Wang Jianping, Liu Yunlong, Zhou Guohua
Abstract excerpt
A novel DNA detection assay was proposed by invasive reaction coupled with molecular beacon assisted strand-displacement signal amplification (IRASA). Target DNAs are firstly hybridized to two probes to initiate invasive reaction to produce amplified flaps. Then these flaps are further amplified by strand-displacement signal amplification. The detection limit was around 0.2 pM.
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