Article
PCR candidate region mismatch scanning: adaptation to quantitative, high-throughput genotyping.
Nucleic acids research - 1 Mar 2001
Beaulieu M, Larson G P, Geller L, Flanagan S D, Krontiris T G
Abstract excerpt
Linkage and association analyses were performed to identify loci affecting disease susceptibility by scoring previously characterized sequence variations such as microsatellites and single nucleotide polymorphisms. Lack of markers in regions of interest, as well as difficulty in adapting various methods to high-throughput settings, often limits the effectiveness of the analyses. We have adapted the Escherichia...
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