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Article

Hormone selectivity in thyroid hormone receptors.

Molecular endocrinology (Baltimore, Md.) - 1 Mar 2001

Wagner R L, Huber B R, Shiau A K, Kelly A, Cunha Lima S T, Scanlan T S, Apriletti J W, Baxter J D, West B L, Fletterick R J

Abstract excerpt

Separate genes encode thyroid hormone receptor subtypes TRalpha (NR1A1) and TRbeta (NR1A2). Products from each of these contribute to hormone action, but the subtypes differ in tissue distribution and physiological response. Compounds that discriminate between these subtypes in vivo may be useful...

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Source

Identifiers

PMID: 11222741
DOI: 10.1210/mend.15.3.0608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11222741-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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