Article
Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer.
Cancer research - 1 Sept 1996
Cascorbi I, Brockmöller J, Mrozikiewicz P M, Bauer S, Loddenkemper R, Roots I
Abstract excerpt
The polymorphic arylamine N-acetyltransferase (NAT2) is supposed to be a susceptibility factor for certain malignancies. A phenotyping study in 389 lung cancer patients revealed a similar distribution of rapid and slow acetylators by the caffeine test to that in 657 reference subjects (odds ratio...
Topics
- Acetylation
- Aged
- Aged, 80 and over
- Amines
- Arylamine N-Acetyltransferase
- Base Sequence
- Disease Susceptibility
- Female
- Genetic Linkage
- Genotype
- Homozygote
- Humans
- Lung Neoplasms
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Phenotype
