Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential association for N-acetyltransferase 2 genotype and phenotype with bladder cancer risk in Chinese population.

Oncotarget - 28 Jun 2016

Quan Lei, Chattopadhyay Koushik, Nelson Heather H, Chan Kenneth K, Xiang Yong-Bing, Zhang Wei, Wang Renwei, Gao Yu-Tang, Yuan Jian-Min

Abstract excerpt

BACKGROUND: N-acetyltransferase 2 (NAT2) is involved in both carcinogen detoxification through hepatic N-acetylation and carcinogen activation through local O-acetylation. NAT2 slow acetylation status is significantly associated with increased bladder cancer risk among European populations, but its association in Asian populations is inconclusive. METHODS: NAT2 acetylation status was determined by both single...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arylamine N-Acetyltransferase
Share to Asian People

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Caffeine

Share to Carcinogens

Share to Gene Expression Regulation, Neoplastic

Share to Odds Ratio

Share to Urinary Bladder Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 27223070
DOI: 10.18632/oncotarget.9475
PMCID: PMC5129988

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential association for N-acetyltransferase 2 genotype and phenotype with bladder cancer risk in Chinese population.PMID 27223070Read ↗

Association between N-Acetyltransferase 2 Polymorphism and Bladder Cancer Risk: a Meta-Analysis in a Single Ethnic Group.Semantic proximity Read ↗

NAT2 slow acetylation and bladder cancer risk: a meta-analysis of 22 case-control studies conducted in the general population.Semantic proximity Read ↗

Association Between N-acetyltransferase 2 Polymorphism and Bladder Cancer Risk: Results From Studies of the Past Decade and a Meta-Analysis.Semantic proximity Read ↗

Relationship between metabolic phenotype of N-acetylation and bladder cancer.Semantic proximity Read ↗

Refinement of the prediction of N-acetyltransferase 2 (NAT2) phenotypes with respect to enzyme activity and urinary bladder cancer risk.Semantic proximity Read ↗

Meta-analysis of the relationship between slow acetylation of N-acetyl transferase 2 and the risk of bladder cancer.Semantic proximity Read ↗

N-acetyltransferase 2 phenotype, occupation, and bladder cancer risk: results from the EPIC cohort.Semantic proximity Read ↗

N-acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk.Semantic proximity Read ↗

Association of NAT2, GSTM1, GSTT1, CYP2A6, and CYP2A13 gene polymorphisms with susceptibility and clinicopathologic characteristics of bladder cancer in Central China.Semantic proximity Read ↗

Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms.Semantic proximity Read ↗

N-acetyltransferase 2 polymorphism is associated with bladder cancer risk: An updated meta-analysis based on 54 case-control studies.Semantic proximity Read ↗

Genetic polymorphisms of N-acetyltransferase 1 and 2 and risk of cigarette smoking-related bladder cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.