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Article

Mutagenic effects of 5-formyluracil on a plasmid vector during replication in Escherichia coli.

International journal of radiation biology - 1 Jan 2001

Miyabe I, Zhang Q M, Sugiyama H, Kino K, Yonei S

Abstract excerpt

PURPOSE: 5-Formyluracil (5-foU) is a major derivative of thymine produced in DNA by ionizing radiation and various chemical oxidants. It has been previously shown that 5-foU in template DNA directs misincorporation of nucleotides by DNA polymerases during in vitro DNA synthesis. The present experiments were designed to understand the biological effects of5-foU in vivo. MATERIALS AND METHODS: The modified base was...

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Source

Identifiers

PMID: 11213350
DOI: 10.1080/095530001453113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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