Longevity and the epsilon2 allele of apolipoprotein E: the Finnish Centenarians Study.

doi:10.1093/gerona/56.2.m75

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Article

Longevity and the epsilon2 allele of apolipoprotein E: the Finnish Centenarians Study.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Feb 2001

Frisoni G B, Louhija J, Geroldi C, Trabucchi M

Abstract excerpt

BACKGROUND: Whether and which genetic factors affect human longevity is unclear. This study assesses the association between the epsilon2 allele of apolipoprotein E (APOE), a putative longevity gene, and extremely old age. METHODS: This study is based on all centenarians living in Finland in 1991. Subjects were 179 persons (28 men and 151 women) aged 100 years and older (response rate, 97%). RESULTS: The...

Topics

Aged
Aged, 80 and over
Alleles
Apolipoprotein E2
Apolipoproteins E
Female
Finland
Gene Frequency
Genotype
Humans
Longevity
Male
Odds Ratio
Regression Analysis
Sex Characteristics

Source

Open in PubMed

Identifiers

PMID: 11213279
DOI: 10.1093/gerona/56.2.m75

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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