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Article

Lack of association of apolipoprotein E allele epsilon 4 with late-onset Alzheimer's disease among Finnish centenarians.

Neurology - 1 May 1995

Sobel E, Louhija J, Sulkava R, Davanipour Z, Kontula K, Miettinen H, Tikkanen M, Kainulainen K, Tilvis R

Abstract excerpt

No association between Alzheimer's disease (AD) and apolipoprotein E type epsilon 4 (ApoE epsilon 4) phenotype was found among centenarians in Finland (N = 179). The data are based on ascertainment of all centenarians in Finland in 1991. All examinations were conducted during 1991. The diagnoses of dementia and AD were based on clinical grounds, conforming to DSM-III-R and NINCDS-ADRDA criteria. The percentage of...

Topics

Age of Onset
Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Cross-Sectional Studies
Female
Finland
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Source

Identifiers

PMID: 7746404
DOI: 10.1212/wnl.45.5.903

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7746404-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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