Article
Aging and genetic variation of plasma apolipoproteins. Relative loss of the apolipoprotein E4 phenotype in centenarians.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jul 1994
Louhija J, Miettinen H E, Kontula K, Tikkanen M J, Miettinen T A, Tilvis R S
Abstract excerpt
We determined the common polymorphism of apolipoprotein E (E2, E3, and E4), apolipoprotein B Xba I polymorphism, and apolipoprotein C-III Sst I polymorphism in almost all Finnish centenarians alive in 1991 (n = 179/185). Plasma lipid and lipoprotein levels in different apolipoprotein genotypes we...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Aging
- Alleles
- Apolipoprotein E4
- Apolipoproteins
- Apolipoproteins E
- Child
- Child, Preschool
- Cholesterol
- Cholesterol, HDL
- Female
- Genetic Variation
- Humans
- Male
- Middle Aged