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Article

Aging and genetic variation of plasma apolipoproteins. Relative loss of the apolipoprotein E4 phenotype in centenarians.

Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jul 1994

Louhija J, Miettinen H E, Kontula K, Tikkanen M J, Miettinen T A, Tilvis R S

Abstract excerpt

We determined the common polymorphism of apolipoprotein E (E2, E3, and E4), apolipoprotein B Xba I polymorphism, and apolipoprotein C-III Sst I polymorphism in almost all Finnish centenarians alive in 1991 (n = 179/185). Plasma lipid and lipoprotein levels in different apolipoprotein genotypes were also measured. In comparison with younger Finnish populations studied previously, the frequency of the...

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Identifiers

PMID: 8018664
DOI: 10.1161/01.atv.14.7.1084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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