Article
Progesterone receptor B gene inactivation and CpG hypermethylation in human uterine endometrial cancer.
Cancer research - 1 Jan 2001
Sasaki M, Dharia A, Oh B R, Tanaka Y, Fujimoto S, Dahiya R
Abstract excerpt
The expressions of two isoforms of human progesterone receptor (PR) are under the control of the two different promoters. Recent studies revealed differences between these isoforms, PRA and PRB, in their expression and function in endometrial cells. Aberrant methylation of normally unmethylated C...
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