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Article

DNA methyltransferase expression in the human endometrium: down-regulation by progesterone and estrogen

7 Feb 2009

Abstract excerpt

BACKGROUND: Epigenetic regulation may be involved in modulation of gene expression during the normal cyclic changes of the human endometrium. We investigated expression of DNA methyltransferases (DNMTs) in endometrium during the menstrual cycle and the influence of sex steroid hormones on DNMT in endometrial stromal cells (ESC) in culture. METHODS: Expression of DNMT1, DNMT3a and DNMT3b was assessed by...

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Share to Endometriosis Research and Treatment
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PMID: 19202141
DOI: 10.1093/humrep/dep015

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