CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis.

doi:10.1158/1055-9965.EPI-08-0875

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2009

Vasilatos Shauna N, Broadwater Gloria, Barry William T, Baker Joseph C, Lem Siya, Dietze Eric C, Bean Gregory R, Bryson Andrew D, Pilie Patrick G, Goldenberg Vanessa, Skaar David, Paisie Carolyn, Torres-Hernandez Alejandro, Grant Tracey L, Wilke Lee G, Ibarra-Drendall Catherine, Ostrander Julie H, D'Amato Nicholas C, Zalles Carola, Jirtle Randy, Weaver Valerie M, Seewaldt Victoria L

Abstract excerpt

BACKGROUND: Only 5% of all breast cancers are the result of BRCA1/2 mutations. Methylation silencing of tumor suppressor genes is well described in sporadic breast cancer; however, its role in familial breast cancer is not known. METHODS: CpG island promoter methylation was tested in the initial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy, Fine-Needle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CpG Islands

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Genes, BRCA2

Share to Premenopause

Share to Receptors, Progesterone

Share to Receptors, Retinoic Acid

Share to Statistics, Nonparametric

Source

Open in PubMed Open full text

Identifiers

PMID: 19258476
DOI: 10.1158/1055-9965.EPI-08-0875
PMCID: PMC2667866

Genes

BRCA1
RARB
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19258476-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis.PMID 19258476Read ↗

Promoter Hypermethylation in Benign Breast Epithelium in Relation to Predicted Breast Cancer RiskSemantic proximity Read ↗

BRCA1 promoter methylation in peripheral blood DNA was identified in sporadic breast cancer and controls.Semantic proximity Read ↗

Association between Lifestyle Factors and CpG Island Methylation in a Cancer-Free PopulationSemantic proximity Read ↗

Detection of Breast Cancer in Nipple Aspirate Fluid by CpG Island HypermethylationSemantic proximity Read ↗

Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors.Semantic proximity Read ↗

Hypermethylation of the breast cancer-associated gene 1 promoter does not predict cytologic atypia or correlate with surrogate end points of breast cancer risk.Semantic proximity Read ↗

Familial and racial determinants of tumour suppressor genes promoter hypermethylation in breast tissues from healthy women.Semantic proximity Read ↗

Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcomeSemantic proximity Read ↗

Quantitative analysis of promoter methylation in exfoliated epithelial cells isolated from breast milk of healthy womenSemantic proximity Read ↗

Quantification of CpG island methylation in progressive breast lesions from normal to invasive carcinoma.Semantic proximity Read ↗

Morphologically Normal-Appearing Mammary Epithelial Cells Obtained from High-Risk Women Exhibit Methylation Silencing of <i>INK4a/ARF</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.