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Article

Promoter Hypermethylation of Progesterone Receptor Isoform B (PR-B) in Endometriosis

1 Apr 2006

Abstract excerpt

The physiological effects of progesterone (P) are mediated by two isoforms of progesterone receptors (PRs): PR-A and PR-B. Progestins have long been used in the treatment of endometriosis but unfortunately the relief of pain is relatively short-term. In addition, about nine percent of women with endometriosis simply do not respond to progestin therapy due to unknown reasons. In fact, a general tendency for...

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Identifiers

PMID: 17965625
DOI: 10.4161/epi.1.2.2766

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