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Article

The effect of DNA methylation inhibitor 5-Aza-2′-deoxycytidine on human endometrial stromal cells

7 Sept 2010

Abstract excerpt

BACKGROUND: Decidualization, the differentiation of endometrial stromal cells is a crucial step for successful implantation of an embryo, development of the placenta and completion of pregnancy to term. Epigenetic mechanisms are thought to be strongly involved in the regulation of processes controlling implantation, placentation, organ formation and foetal growth. Recent studies suggest that decreased DNA...

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PMID: 20823114
DOI: 10.1093/humrep/deq238

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