Article
Analysis of HLA haplotypes in autoimmune hepatitis type 1: identifying the major susceptibility locus.
Human immunology - 1 Feb 2001
Goldberg A C, Bittencourt P L, Mougin B, Cançado E L, Porta G, Carrilho F, Kalil J
Abstract excerpt
Susceptibility to autoimmune hepatitis type I (AIH-1) has been associated with HLA-DR3, DR52, and DR4 antigens in Caucasian and Oriental patients. However, in Brazil, disease susceptibility is primarily linked to DR13 and DR52. In this highly admixed population, we find different DR13-associated haplotypes, presenting a unique opportunity to discriminate relevant genes within a tightly linked genomic region. To...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
