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Article

Determination of SNP allele frequencies in pooled DNAs by primer extension genotyping and denaturing high-performance liquid chromatography.

Journal of biochemical and biophysical methods - 30 Jan 2001

Giordano M, Mellai M, Hoogendoorn B, Momigliano-Richiardi P

Abstract excerpt

By testing DNA pools rather than single samples the number of tests for a case-control association study can be decreased to only two for each marker: one on the patient and one on the control pool. A fundamental requirement is that each pool represents the frequency of the markers in the corresponding population beyond the influence of experimental errors. Consequently the latter must be carefully determined. To...

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PMID: 11179766
DOI: 10.1016/s0165-022x(00)00156-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Determination of SNP allele frequencies in pooled DNAs by primer extension genotyping and denaturing high-performance liquid chromatography.PMID 11179766Read ↗

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