Article
Absence of p51 alteration in human ovarian cancer.
International journal of oncology - 1 Mar 2001
Shinozaki H, Okamoto A, Shimizu K, Saito M, Yokota J, Ochiai K
Abstract excerpt
The p51 gene encodes a protein with significant homology to p53, thus, it is a candidate tumor suppressor gene. To investigate the involvement of the p51 gene in human ovarian carcinogenesis, p51 gene alterations were examined in primary ovarian cancers and ovarian cancer cell lines. Mutation analysis of the p51 gene was performed in 40 primary ovarian cancers and 6 ovarian cancer cell lines using the PCR-SSCP...
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