Article
Absence of p51 mutation in human hepatocellular carcinoma.
Cancer letters - 1 Feb 2000
Hamada K, Koyama T, Shimizu K, Ikawa S, Kawate S, Yokota J, Ohwada S, Morishita Y
Abstract excerpt
The p51 gene encodes a protein with significant homology to p53. To investigate the involvement of the p51 gene in human hepatocarcinogenesis, mutation analysis of the p51 gene was performed in 54 cases of hepatocellular carcinoma (HCC). No mutations causing amino acid substitutions or frameshifts were found by polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP) analysis of the entire...
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