Article
Analysis of 2 antiapoptotic factors in gliomas: bcl-2 overexpression and p53 mutations.
Archives of pathology & laboratory medicine - 1 Feb 2001
Rodriguez-Pereira C, Suarez-Peñaranda J M, Barros F, Sobrido M J, Vazquez-Salvado M, Forteza J
Abstract excerpt
BACKGROUND: p53 mutations and immunoreactivity have been described in human gliomas. During the past few years, some authors have found bcl-2 overexpression in astrocytomas, although their correlation with histological grade is a matter of disagreement. A relation between bcl-2 overexpression and p53 immunoreactivity has also been suggested. OBJECTIVES: To analyze the frequency of presentation of bcl-2 and p53,...
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