Article
The role of apoptosis, cell proliferation index, bcl-2, and p53 in glioblastoma prognosis.
Arquivos de neuro-psiquiatria - 1 Jun 2004
Ribeiro Marlise de Castro, Coutinho Lígia M Barbosa, Hilbig Arlete
Abstract excerpt
UNLABELLED: Glioblastoma is the most common neuroectodermic tumor. It is also the most malignant one. Many genetic changes are found in glioblastomas, among them, the presence of oncoproteins p53 and blc-2, as well as a high mitotic level and the presence of apoptosis. The utility of such findings through immunohistochemistry for the prognosis of patients remains uncertain. Our objectives in this study were to...
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