Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic factors in malignant glioma: influence of the overexpression of oncogene and tumor-suppressor gene products on survival.

Journal of neuro-oncology - 1 Oct 1997

Rainov N G, Dobberstein K U, Bahn H, Holzhausen H J, Lautenschläger C, Heidecke V, Burkert W

Abstract excerpt

Despite the use of multimodal therapy, higher-grade glioma is still uniformly fatal in the adult population. There is a considerable difference between the length of survival in each given patient, even within the same tumor type and malignancy grade group, suggesting that there are factors that might differentially influence outcome. To identify such factors, 107 patients with anaplastic or malignant glioma were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Genes, Tumor Suppressor

Share to Immunohistochemistry

Share to Mutation

Share to Oncogenes

Share to Prognosis

Source

Identifiers

PMID: 9266437
DOI: 10.1023/a:1005841520514

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic factors in malignant glioma: influence of the overexpression of oncogene and tumor-suppressor gene products on survival.PMID 9266437Read ↗

Gene amplification as a prognostic factor in primary and secondary high-grade malignant gliomas.Semantic proximity Read ↗

Prognostic value of epidermal growth factor receptor amplification and EGFRvIII in glioblastoma: meta-analysis.Semantic proximity Read ↗

Modeling prognosis for patients with malignant astrocytic gliomas: Quantifying the expression of multiple genetic markers and clinical variablesSemantic proximity Read ↗

Analysis of mdm2 and p53 gene alterations in glioblastomas and its correlation with clinical factors.Semantic proximity Read ↗

Prognostic significance of co-overexpression of the EGFR/IGFBP-2/HIF-2A genes in astrocytomasSemantic proximity Read ↗

Mutations in Rb1 pathway-related genes are associated with poor prognosis in anaplastic astrocytomas.Semantic proximity Read ↗

Worse Outcome in Primary Glioblastoma Multiforme With Concurrent Epidermal Growth Factor Receptor and p53 AlterationSemantic proximity Read ↗

Up-regulation of EphA2 and down-regulation of EphrinA1 are associated with the aggressive phenotype and poor prognosis of malignant glioma.Semantic proximity Read ↗

Analysis of 2 antiapoptotic factors in gliomas: bcl-2 overexpression and p53 mutations.Semantic proximity Read ↗

PTEN Mutation, EGFR Amplification, and Outcome in Patients With Anaplastic Astrocytoma and Glioblastoma MultiformeSemantic proximity Read ↗

Epidermal Growth Factor Receptor Gene Amplification and Protein Expression in Glioblastoma MultiformeSemantic proximity Read ↗

Aberrant p53, mdm2, and proliferation differ in glioblastomas from long-term compared with typical survivors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.