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Article

K-ras mutations in the bile of patients with primary sclerosing cholangitis.

Gut - 1 Mar 2001

Kubicka S, Kühnel F, Flemming P, Hain B, Kezmic N, Rudolph K L, Manns M, Meier P N

Abstract excerpt

BACKGROUND AND AIMS: The development of cholangiocarcinoma (CCC) is a complication of primary sclerosing cholangitis (PSC). To date, no reliable factors have been described which can define those PSC patients at high risk for the development of CCC and the clinical diagnosis of CCC in PSC patients is difficult. Therefore, molecular markers of cholangiocarcinogenesis, such as K-ras mutations, may improve the early...

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Share to Bile
Share to Bile Duct Neoplasms
Share to Bile Ducts, Intrahepatic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cholangiocarcinoma

Share to Cholangitis, Sclerosing

Share to Genes, ras

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Source

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Identifiers

PMID: 11171833
DOI: 10.1136/gut.48.3.403
PMCID: PMC1760156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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K-ras mutations in the bile of patients with primary sclerosing cholangitis.PMID 11171833Read ↗

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