Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 overexpression and K-ras gene mutations in primary sclerosing cholangitis-associated biliary tract cancer.

Journal of hepato-biliary-pancreatic surgery - 1 Jan 2000

Ahrendt S A, Rashid A, Chow J T, Eisenberger C F, Pitt H A, Sidransky D

Abstract excerpt

Cholangiocarcinoma occurs frequently in patients with primary sclerosing cholangitis (PSC). We evaluated the incidence and prognostic significance of p53 protein overexpression and K-ras gene mutations in patients with biliary tract cancer and PSC. p53 protein expression was determined in specimens from 12 patients with biliary tract cancer, using the antibody, D07. K-ras mutations were detected using DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Duct Neoplasms
Share to Bile Ducts, Intrahepatic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carcinoma, Small Cell

Share to Cholangiocarcinoma

Share to Cholangitis, Sclerosing

Share to Gallbladder Neoplasms

Share to Genes, ras

Share to Survival Rate

Source

Identifiers

PMID: 11180865
DOI: 10.1007/s005340070039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 overexpression and K-ras gene mutations in primary sclerosing cholangitis-associated biliary tract cancer.PMID 11180865Read ↗

Cholangiocarcinoma in primary sclerosing cholangitis: K-ras mutations and Tp53 dysfunction are implicated in the neoplastic development.Semantic proximity Read ↗

K-ras mutations in the bile of patients with primary sclerosing cholangitis.Semantic proximity Read ↗

The Role of K-Ras and P53 in Biliary Tract Carcinoma.Semantic proximity Read ↗

Usefulness of p53 gene mutations in the supernatant of bile for diagnosis of biliary tract carcinoma: comparison with K- ras mutation.Semantic proximity Read ↗

K-ras codon 12 and p53 mutations in biopsy specimens and bile from biliary tract cancers.Semantic proximity Read ↗

Low frequency of p53 and ras mutations in bile of patients with hepato-biliary disease: a prospective study in more than 100 patients.Semantic proximity Read ↗

TP53 mutations and mdm2 protein overexpression in cholangiocarcinomas.Semantic proximity Read ↗

Analysis of ras gene mutations in human hepatic malignant tumors by polymerase chain reaction and direct sequencing.Semantic proximity Read ↗

Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer.Semantic proximity Read ↗

Ki-ras and p53 mutations in pancreatic ductal adenocarcinoma.Semantic proximity Read ↗

Analysis of microsatellite instability, K-ras gene mutation and p53 protein overexpression in intrahepatic cholangiocarcinoma.Semantic proximity Read ↗

Analysis of ras gene mutations in biliary and pancreatic tumors by polymerase chain reaction and direct sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.