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Article

In vivo activities of mutants of vascular endothelial growth factor (VEGF) with differential in vitro activities.

International journal of cancer - 1 Feb 2001

Leenders W, van Altena M, Lubsen N, Ruiter D, De Waal R

Abstract excerpt

VEGF mutants in which Cys51 or Cys60 are converted into a serine are poor inducers of proliferation in human umbilical vein endothelial cells, but they have wild-type activity in the Miles vascular permeability assay. To assess the contribution of proliferation vs. other VEGF activities such as vascular permeability, to tumor angiogenesis and growth, C127I cells, transfected with BPV-based expression plasmids...

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Source

Identifiers

PMID: 11169955
DOI: 10.1002/1097-0215(200002)9999:9999<::aid-ijc1052>3.3.co;2-n

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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