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Article

VEGF<sub>165</sub>b overexpression restores normal glomerular water permeability in VEGF<sub>164</sub>-overexpressing adult mice

19 Jul 2012

Abstract excerpt

Vascular endothelial growth factor (VEGF)-A, a family of differentially spliced proteins produced by glomerular podocytes, maintains glomerular filtration barrier function. The expression of VEGF molecules is altered in human nephropathy. We aimed to determine the roles of the angiogenic VEGF(164) isoform, and the antiangiogenic VEGF(165)b isoform in mature, adult glomeruli in vivo using conditional, inducible...

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PMID: 22811490
DOI: 10.1152/ajprenal.00410.2011

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VEGF<sub>165</sub>b overexpression restores normal glomerular water permeability in VEGF<sub>164</sub>-overexpressing adult micePMID 22811490Read ↗

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