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Article

IL-13 overexpression predisposes to anaphylaxis following antigen sensitization.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2001

Fallon P G, Emson C L, Smith P, McKenzie A N

Abstract excerpt

Anaphylaxis represents an extreme form of allergic reaction. This acute-phase component of allergy and asthma is triggered by allergen-induced degranulation of mast cells following the cross-linking of cell surface-bound, allergen-specific IgE, resulting in the liberation of inflammatory mediators and the development of bronchoconstriction. We used IL-13 transgenic mice to investigate the role of this Th2...

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Source

Identifiers

PMID: 11160336
DOI: 10.4049/jimmunol.166.4.2712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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