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Article

Oral anaphylaxis to peanut in a mouse model is associated with gut permeability but not with Tlr4 or Dock8 mutations.

The Journal of allergy and clinical immunology - 1 Jan 2022

Gertie Jake A, Zhang Biyan, Liu Elise G, Hoyt Laura R, Yin Xiangyun, Xu Lan, Long Lauren L, Soldatenko Arielle, Gowthaman Uthaman, Williams Adam, Eisenbarth Stephanie C

Abstract excerpt

BACKGROUND: The etiology of food allergy is poorly understood; mouse models are powerful systems to discover immunologic pathways driving allergic disease. C3H/HeJ mice are a widely used model for the study of peanut allergy because, unlike C57BL/6 or BALB/c mice, they are highly susceptible to oral anaphylaxis. However, the immunologic mechanism of this strain's susceptibility is not known. OBJECTIVE: We aimed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34051223
DOI: 10.1016/j.jaci.2021.05.015
PMCID: PMC8626534

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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