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Article

Mice lacking the chemokine receptor CCR1 show increased susceptibility to Toxoplasma gondii infection.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2001

Khan I A, Murphy P M, Casciotti L, Schwartzman J D, Collins J, Gao J L, Yeaman G R

Abstract excerpt

Chemokines are critical for the recruitment of effector immune cells to sites of infection. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation. In the present study, we tested the susceptibility of CCR1 knockout mice to infection with the obligate intracellular protozoan parasite Toxoplasma gondii. In comparison with parental wild-type mice, CCR1(-/-) mice exhibited...

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Source

Identifiers

PMID: 11160241
DOI: 10.4049/jimmunol.166.3.1930

Genes

CCR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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