Article
Genetic analysis of host resistance to intracellular pathogens: lessons from studies of Toxoplasma gondii infection.
Microbes and infection - 1 Apr 2006
Yap George S, Shaw Michael H, Ling Yun, Sher Alan
Abstract excerpt
Cell-mediated immunity to Toxoplasma gondii establishes and maintains a balanced host-pathogen relationship. Recent analyses using spontaneous and genetically engineered mouse mutants have yielded a clearer picture of factors positively and negatively regulating the host immune response and a better understanding of cytokine-inducible intracytoplasmic mechanisms that lead to intracellular pathogen suppression and...
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