Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CCR5 is essential for NK cell trafficking and host survival following Toxoplasma gondii infection.

PLoS pathogens - 1 Jun 2006

Khan Imtiaz A, Thomas Seddon Y, Moretto Magali M, Lee Frederick S, Islam Sabina A, Combe Crescent, Schwartzman Joseph D, Luster Andrew D

Abstract excerpt

The host response to intracellular pathogens requires the coordinated action of both the innate and acquired immune systems. Chemokines play a critical role in the trafficking of immune cells and transitioning an innate immune response into an acquired response. We analyzed the host response of mice deficient in the chemokine receptor CCR5 following infection with the intracellular protozoan parasite Toxoplasma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adoptive Transfer
Share to DNA, Protozoan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-12

Share to Killer Cells, Natural

Share to Receptors, CCR5

Share to Survival

Share to Toxoplasma

Share to Toxoplasmosis

Source

Open in PubMed Open full text

Identifiers

PMID: 16789839
DOI: 10.1371/journal.ppat.0020049
PMCID: PMC1475660

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CCR5 is essential for NK cell trafficking and host survival following Toxoplasma gondii infection.PMID 16789839Read ↗

Mice lacking the chemokine receptor CCR1 show increased susceptibility to Toxoplasma gondii infection.Semantic proximity Read ↗

Ccr5 deficiency regulates the proliferation and trafficking of natural killer cells under physiological conditions.Semantic proximity Read ↗

The role of CCR5 in Chagas disease - a systematic review.Semantic proximity Read ↗

CCR5 Plays a Critical Role in the Development of Myocarditis and Host Protection in Mice Infected withTrypanosoma cruziSemantic proximity Read ↗

CXCR2 deficiency confers impaired neutrophil recruitment and increased susceptibility during Toxoplasma gondii infection.Semantic proximity Read ↗

Impaired innate immunity in mice deficient in interleukin-1 receptor-associated kinase 4 leads to defective type 1 T cell responses, B cell expansion, and enhanced susceptibility to infection with Toxoplasma gondii.Semantic proximity Read ↗

Genetic Mapping of Pathogenesis Determinants in Toxoplasma gondiiSemantic proximity Read ↗

Opposing effects of CXCR3 and CCR5 deficiency on CD8+ T cell-mediated inflammation in the central nervous system of virus-infected mice.Semantic proximity Read ↗

CCR6 is essential for effective immunity against <i>Mycobacterium tuberculosis</i> infection in miceSemantic proximity Read ↗

ROP39 is an Irgb10-specific parasite effector that modulates acute Toxoplasma gondii virulenceSemantic proximity Read ↗

The Dual Role of CCR5 in the Course of Influenza Infection: Exploring Treatment Opportunities.Semantic proximity Read ↗

The Polymorphic Pseudokinase ROP5 Controls Virulence in Toxoplasma gondii by Regulating the Active Kinase ROP18Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.