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Article

Monitoring Resistance to Human Immunodeficiency Virus Type 1 Protease Inhibitors by Pyrosequencing

1 Feb 2001

Abstract excerpt

The emergence of drug-resistant viral variants is the inevitable consequence of incomplete suppression of human immunodeficiency virus type 1 (HIV-1) replication during treatment with antiretroviral drugs. Sequencing to determine the resistance profiles of these variants has become increasingly important in the clinical management of HIV-1 patients, both in the initial design of a therapeutic plan and in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11158091
DOI: 10.1128/jcm.39.2.464-473.2001

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