Article

Extremely fast and accurate open modification spectral library searching of high-resolution mass spectra using feature hashing and graphics processing units

2019-05-05

Abstract excerpt

Open modification searching (OMS) is a powerful search strategy to identify peptides with any type of modification. OMS works by using a very wide precursor mass window to allow modified spectra to match against their unmodified variants, after which the modification types can be inferred from the corresponding precursor mass differences. A disadvantage of this strategy, however, is the large computational cost, b...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d197829c-38e5-561a-8f61-ea11be87088e
DOI: 10.1101/627497

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Extremely fast and accurate open modification spectral library searching of high-resolution mass spectra using feature hashing and graphics processing unitsDOI 10.1101/627497Read

Fast open modification spectral library searching through approximate nearest neighbor indexingSemantic proximity Read

Large-scale tandem mass spectrum clustering using fast nearest neighbor searchingSemantic proximity Read

Fast alignment of mass spectra in large proteomics datasets, capturing dissimilarities arising from multiple complex modifications of peptidesSemantic proximity Read

SpecGlob: rapid and accurate alignment of mass spectra differing from their peptide models by several unknown modificationsSemantic proximity Read

Interpreting Mass Spectra Differing from Their Peptide Models by Several ModificationsSemantic proximity Read

Discovery of non-canonical proteins through modification-aware proteogenomicsSemantic proximity Read

Open-pFind enables precise, comprehensive and rapid peptide identification in shotgun proteomicsSemantic proximity Read

Fast multi-blind modification search through tandem mass spectrometry.Semantic proximity Read

Mining for ions: diagnostic feature detection in MS/MS spectra of post-translationally modified peptidesSemantic proximity Read

Open Modification Searching of SARS-CoV-2–Human Protein Interaction Data Reveals Novel Viral Modification SitesSemantic proximity Read

A High-Quality Acetylation Dataset Reveals Modest Data Requirements for Transfer Learning to Identify Little Studied Post-Translational ModificationsSemantic proximity Read

Spectrum graph-based de-novo sequencing algorithm MaxNovo achieves high peptide identification rates in collisional dissociation MS/MS spectraSemantic proximity Read