Article
Error tolerant searching of uninterpreted tandem mass spectrometry data.
Proteomics - 1 Oct 2002
Creasy David M, Cottrell John S
Abstract excerpt
An error tolerant mode for database matching of uninterpreted tandem mass spectrometry data is described. Selected database entries are searched without enzyme specificity, using a comprehensive list of chemical and post-translational modifications, together with a residue substitution matrix. The modifications are tested serially, to avoid the catastrophic loss of discrimination that would occur if all the...
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