Article

Interpreting Mass Spectra Differing from Their Peptide Models by Several Modifications

2021-12-08

Abstract excerpt

<h4>Background: </h4> In proteomics, mass spectra representing peptides carrying multiple unknown modifications are particularly difficult to interpret. This issue results in a large number of unidentified spectra. <h4>Methods:</h4> We developed SpecGlob, a dynamic programming algorithm that aligns pairs of spectra – each pair given by a Peptide-Spectrum Match (PSM) – provided by any Open Modification Search (OMS)...

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Literature Corpus work: f82eaffd-4434-5ef1-a0b5-7674464008ee
DOI: 10.21203/rs.3.rs-1133992/v1

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